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國立臺灣大學與中央研究院聯合辦公室

優良成果研究成果

歷年計畫優良成果:以微流道整合表面電漿子共振晶片開發微型聚合酶鏈鎖反應高通量快速檢驗裝置

110-111年度「國立臺灣大學與中央研究院創新性合作計畫」

 

以微流道整合表面電漿子共振晶片開發微型聚合酶鏈鎖反應高通量快速檢驗裝置
Development of microscale PCR high-throughput rapid test device by integrating microfluidic and surface plasma resonance chip.

 

 

計畫成員

 

國立臺灣大學應用力學所 沈弘俊 教授
中央研究院應科中心 魏培坤 研究員

計畫執行期間:2021.1.1 – 2022.12.31

 

 

優良研究成果

 

(1) Journal paper

 

Han-Yun Hsieh+, Ray Chang+, Yung-Yu Huang, Po-Han Juan, Hidetoshi Tahara, Kuan-Yi Lee, Ming-Han Tsai, Pei-Kuen Wei*, Horn-Jiunn Sheen*, and Yu-Jui Fan* “Continuous polymerase chain reaction microfluidics integrated with a gold-capped nanoslit sensing chip for Epstein-Barr virus detection” Biosensors and Bioelectronics, 195, 113672, 2022 (DOI: 10.1016/j.bios.2021.113672) [2020 IF=10.618, 3/83 in CHEMISTRY, ANALYTICAL]

 

(2) Conference paper 

(a) Han-Yun Hsieh+, Ray Chang+, Yung-Yu Huang, Pei-Kuen Wei*, Horn-Jiunn Sheen*,and Yu-Jui Fan* ”LMP1gene detection with polymerase chain reaction in microfluidic chip combined with nanoslit surface plasmon resonance sensor” ICSS 2021. Oral Presentation.
 

(b) Han-Yun Hsieh, Ray Chang, Ming-Han Tsai, Jo-Ning Hung, Shu-Cheng Lo, Kuan-Yi Lee, Wei-Hung Chen, Yu-Jui Fan*, Pei-Kuen Wei*, and Horn-Jiunn Sheen* “A Duplex PCR Biosensor for the Simultaneous Detection of LMP1 and COVID-19” ICSS 2022. Poster Presentation.

 

(3) Patent List

 

一種聚合酶連鎖反應結合表面電漿共振裝置用於核酸檢測 (台灣發明專利申請案06A-211201-TW)

 

(4) List of Personal Achievements of the PIs

  • Honors/Awards
    (a) ICSS 2021 oral presentation honorable award

    Han-Yun Hsieh+, Ray Chang+, Yung-Yu Huang, Pei-Kuen Wei*, Horn-Jiunn Sheen*, and Yu-Jui Fan* ”LMP1gene detection with polymerase chain reaction in microfluidic chip combined with nanoslit surface plasmon resonance sensor”

    (b) Distinguished Paper Award
    Han-Yun Hsieh+, Ray Chang+, Yung-Yu Huang, Po-Han Juan, Hidetoshi Tahara, Kuan-Yi Lee, Ming-Han Tsai, Pei-Kuen Wei*, Horn-Jiunn Sheen*, and Yu-Jui Fan* “Continuous polymerase chain reaction microfluidics integrated with a gold-capped nanoslit sensing chip for. Epstein-Barr virus detection”

 

  • Invited Talk:  IEEE NanoMed 2021
    Han-Yun Hsieh+, Ray Chang+, Yung-Yu Huang, Po-Han Juan, Hidetoshi Tahara,

    Kuan-Yi Lee, Ming-Han Tsai, Pei-Kuen Wei*, Horn-Jiunn Sheen*, and Yu-Jui

    Fan* “Continuous polymerase chain reaction microfluidics integrated with a

    gold-capped nanoslit sensing chip for Epstein-Barr virus detection”