歷年計畫優良成果:開發具轉移型腫瘤靶向性之近紅外光長餘輝奈米材料用於肺癌化療

25 4 月

108-109年度「國立臺灣大學與中央研究院創新性合作計畫」

開發具轉移型腫瘤靶向性之近紅外光長餘輝奈米材料用於肺癌化療
Development of Metastatic Tumor-Targeting NIR Persistent Luminescence Nanomaterials to Chemotherapy for Lung Cancer

 

計畫成員

國立臺灣大學化學系 劉如熹 教授
中央研究院基因體中心 蕭宏昇 研究員

計畫執行期間:2019.1.1 – 2020.12.31

 

優良研究成果

台大化學劉如熹教授與中研院基因體中心蕭宏昇教授於108–109年度進行創新性合作計畫「開發具轉移型腫瘤靶向性之近紅外光長餘輝奈米材料用於肺癌化療」,因執行本計畫延伸出之優良研究成果主要以發表於國際期刊為主。近三年共發表兩篇研究文獻(article)與五篇文獻回顧(reivew),如下表所示。

發表於國際著名期刊

形式 亮點 文章標題
1 Article 紅外奈米粒子用於腦瘤治療 Long-Term Near-Infrared Signal Tracking of the Therapeutic Changes of Glioblastoma Cells in Brain Tissue with Ultrasound-Guided Persistent Luminescent Nanocomposites. ACS Appl. Mater. Interfaces 2021, 13, 6099–6108.
2 Article 紅外奈米粒子促進植物生長 Near‐Infrared Nanophosphor Embedded in Mesoporous Silica Nanoparticle with High Light‐Harvesting Efficiency for Dual Photosystem Enhancement. Angew. Chem. Ed. Int. 2021, 60, 6955–6959.
3 Review 碳量子點用於癌症治療 Natural Carbon Nanodots for Theoretical Evaluation and Theranostic Cancer Application. Pharmarceutics 2021, 13, 1874.
4 Review 複合奈米粒子用於腦瘤治療 Progress and Viewpoints of Multifunctional Composite Nanomaterials for Glioblastoma Theranostics. Pharmarceutics 2022, 14, 456.
5 Review 奈米螢光粉應用於紅外一二區治療中近紅外之光學進展 The Optical Research Progress of Nanophosphors Composed of Transition Elements in the Fourth Period of Near-Infrared Windows I and II for Deep-Tissue Theranostics. Nanoscale 2022, 14,7123–7136.
6 Review 奈米螢光粉於紅外一二區生物治療之應用 Near-Infrared Windows I and II Phosphors for Theranostic Applications: Spectroscopy, Bioimaging, and Light-Emitting Diode Photobiomodulation. Adv. Opt. Mater. 2022, 2202061.
7 Review 單原子催化應用於癌症診斷治療 Tunable Single-Atom Nanozyme Catalytic System for Biological Applications of Therapy and Diagnosis. Mater. Today. Adv. 2023, 17, 100342.